The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2019
Filed:
Jul. 18, 2017
Applicant:
Celestra Life Science Llc, Richmond, VA (US);
Inventors:
Allen J. Lee, Short Hills, NJ (US);
Jason J. Lee, Short Hills, NJ (US);
David M. Lu, Richmond, NJ (US);
Ruey-Min Lee, Short Hills, NJ (US);
Assignee:
CELESTRA LIFE SCIENCE LLC, Richmond, VA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/553 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 31/553 (2013.01); G01N 33/5011 (2013.01);
Abstract
The methods, compositions, and kits of the invention are related to the discovery that lestaurtinib reduces levels and pathway activity of an SPOP substrate. Accordingly, described herein are methods and compositions for the use of lestaurtinib in downregulating one or more SPOP substrates or signaling pathway activities thereof in a subject in need thereof.