The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2019
Filed:
Jun. 20, 2013
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Robert H. Weiss, Vacaville, CA (US);
Bruce D. Hammock, Davis, CA (US);
Hiromi Inoue Wettersten, Sacramento, CA (US);
Sung Hee Hwang, Davis, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); A61K 31/4439 (2006.01); A61K 31/17 (2006.01); A61K 31/192 (2006.01); A61K 31/277 (2006.01); A61P 35/02 (2006.01); A61P 35/00 (2006.01); A61K 31/4412 (2006.01); A61K 45/06 (2006.01); A61K 31/196 (2006.01); A61K 31/675 (2006.01); A61K 31/704 (2006.01); A61K 33/24 (2019.01);
U.S. Cl.
CPC ...
A61K 31/4412 (2013.01); A61K 31/17 (2013.01); A61K 31/196 (2013.01); A61K 31/277 (2013.01); A61K 31/44 (2013.01); A61K 31/4439 (2013.01); A61K 31/675 (2013.01); A61K 31/704 (2013.01); A61K 33/24 (2013.01); A61K 45/06 (2013.01);
Abstract
The present invention provides sorafenib analogs for use in a method of treating a disease mediated by p21, said method comprising administering to a subject in need thereof a therapeutically effective amount of a compound of formula I. The present invention also provides methods of inhibiting p21 in a cell comprising contacting the cell with an effective amount of a compound of formula I.