logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10449182 B1

PDFFull Text
Date of Patent:
Oct. 22, 2019

Filed:

Jun. 20, 2013

Sorafenib derivatives as p21 inhibitors

Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Robert H. Weiss, Vacaville, CA (US);

Bruce D. Hammock, Davis, CA (US);

Hiromi Inoue Wettersten, Sacramento, CA (US);

Sung Hee Hwang, Davis, CA (US);

Assignee:

The Regents of the University of California, Oakland, CA (US);

Attorney:

Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.

Primary Examiner:

Irina Neagu

Int. Cl.
CPC ...
A61K 31/44 (2006.01); A61K 31/4439 (2006.01); A61K 31/17 (2006.01); A61K 31/192 (2006.01); A61K 31/277 (2006.01); A61P 35/02 (2006.01); A61P 35/00 (2006.01); A61K 31/4412 (2006.01); A61K 45/06 (2006.01); A61K 31/196 (2006.01); A61K 31/675 (2006.01); A61K 31/704 (2006.01); A61K 33/24 (2019.01);
U.S. Cl.
CPC ...
A61K 31/4412 (2013.01); A61K 31/17 (2013.01); A61K 31/196 (2013.01); A61K 31/277 (2013.01); A61K 31/44 (2013.01); A61K 31/4439 (2013.01); A61K 31/675 (2013.01); A61K 31/704 (2013.01); A61K 33/24 (2013.01); A61K 45/06 (2013.01);
Abstract

The present invention provides sorafenib analogs for use in a method of treating a disease mediated by p21, said method comprising administering to a subject in need thereof a therapeutically effective amount of a compound of formula I. The present invention also provides methods of inhibiting p21 in a cell comprising contacting the cell with an effective amount of a compound of formula I.

Find Patent Forward Citations

Quick Actions:

Weiss, Robert. (2019). Sorafenib derivatives as p21 inhibitors (U.S. Patent No. 10449182). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10449182

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…