The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2019
Filed:
Aug. 19, 2011
Applicants:
Varghese John, San Francisco, CA (US);
Dale E. Bredesen, Novato, CA (US);
Inventors:
Varghese John, San Francisco, CA (US);
Dale E. Bredesen, Novato, CA (US);
Assignee:
Buck Institute for Research on Aging, Novato, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4035 (2006.01); A61K 31/05 (2006.01); A61K 31/145 (2006.01); A61K 31/5513 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4035 (2013.01); A61K 31/05 (2013.01); A61K 31/145 (2013.01); A61K 31/5513 (2013.01);
Abstract
The invention provides compositions and methods for the treatment of mild cognitive impairment (MCI), and for inhibiting, reducing, delaying and/or preventing the progression of MCI to Alzheimer's disease. The methods entail administering an effective amount of one or more compounds selected from the group consisting of tropisetron, disulfuram, honokiol and nimetazepam. The methods also are useful for prophylactic and therapeutic treatment of amyloidogenic diseases, including Alzheimer's disease.