The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 22, 2019

Filed:

Jul. 21, 2016
Applicants:

Massachusetts Institute of Technology, Cambridge, MA (US);

Nuvu Llc, Cambridge, MA (US);

Inventors:

Nir Grossman, Loerrach, DE;

David Wang, Cambridge, MA (US);

Edward Boyden, Chestnut Hill, MA (US);

Assignees:

Massachusetts Institute of Technology, Cambridge, MA (US);

NuVu LLC, Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06F 17/14 (2006.01); A61B 5/00 (2006.01); A61B 5/04 (2006.01); A61B 5/11 (2006.01); A61N 5/06 (2006.01); A61N 7/00 (2006.01); A61B 5/0476 (2006.01);
U.S. Cl.
CPC ...
A61B 5/4836 (2013.01); A61B 5/04001 (2013.01); A61B 5/0476 (2013.01); A61B 5/1101 (2013.01); A61B 5/7253 (2013.01); A61B 5/7257 (2013.01); A61N 5/0622 (2013.01); A61N 7/00 (2013.01); G06F 17/14 (2013.01); A61N 2005/063 (2013.01); A61N 2007/0021 (2013.01);
Abstract

A neuromodulator accurately measures—in real time and over a range of frequencies—the instantaneous phase and amplitude of a natural signal. For example, the natural signal may be an electrical signal produced by neural tissue, or a motion such as a muscle tremor. The neuromodulator generates signals that are precisely timed relative to the phase of the natural signal. For example, the neuromodulator may generate an exogenous signal that is phase-locked with the natural signal. Or, for example, the neuromodulator may generate an exogenous signal that comprises short bursts which occur only during a narrow phase range of each period of an oscillating natural signal. The neuromodulator corrects distortions due to Gibbs phenomenon. In some cases, the neuromodulator does so by applying a causal filter to a discrete Fourier transform in the frequency domain, prior to taking an inverse discrete Fourier transform.


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