The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 22, 2019

Filed:

Oct. 28, 2016
Applicants:

Y-biologics Inc., Daejeon, KR;

Industry-academic Cooperation Foundation, Yonsei University, Seoul, KR;

Inventors:

Young Woo Park, Daejeon, KR;

Bum-chan Park, Daejeon, KR;

Bong-soo Cha, Seoul, KR;

Yong Ho Lee, Seoul, KR;

Jung Chae Lim, Daejeon, KR;

Young-gyu Cho, Daejeon, KR;

Joong Kyu Kim, Daejeon, KR;

Jae Eun Park, Daejeon, KR;

Seok Ho Yoo, Daejeon, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 38/18 (2006.01); C07K 14/47 (2006.01); C07K 14/475 (2006.01); C07K 19/00 (2006.01); A23L 33/17 (2016.01); A61K 47/68 (2017.01);
U.S. Cl.
CPC ...
A23L 33/17 (2016.08); A61K 38/1709 (2013.01); A61K 38/18 (2013.01); A61K 47/68 (2017.08); C07K 14/4713 (2013.01); C07K 19/00 (2013.01); C07K 14/475 (2013.01); C07K 2319/30 (2013.01);
Abstract

The present invention relates to compositions and methods for treating fatty liver, steatohepatitis, or liver cirrhosis as well as insulin resistance and aging by administration of a DLK1-Fc fusion protein constructed by conjugation of an extracellular domain of DLK1 or a fragment thereof with a human antibody Fc region. Also provided are health functional foods containing a DLK1-Fc fusion protein constructed by conjugation of an extracellular domain of DLK1 (delta-like 1 homolog) or a fragment thereof with a human antibody Fc region as an active ingredient.


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