The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 15, 2019

Filed:

Jun. 22, 2016
Applicants:

Abbott Laboratories, Abbott Park, IL (US);

Icahn School of Medicine AT Mount Sinai, New York, NY (US);

Inventors:

Robert Ziemann, Abbott Park, IL (US);

April Ahlberg, Abbott Park, IL (US);

David Hawksworth, Abbott Park, IL (US);

Bryan Tieman, Abbott Park, IL (US);

A. Scott Muerhoff, Abbott Park, IL (US);

Christopher Marohnic, Abbott Park, IL (US);

Kathy Otis, Abbott Park, IL (US);

Andrea Branch, New York, NY (US);

Francis Eng, New York, NY (US);

Assignees:

ABBOTT LABORATORIES, Abbott Park, IL (US);

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/576 (2006.01); C07K 16/10 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5767 (2013.01); C07K 16/109 (2013.01); C07K 2317/34 (2013.01); C07K 2317/56 (2013.01); C07K 2317/92 (2013.01); G01N 2333/186 (2013.01); G01N 2469/10 (2013.01); G01N 2800/52 (2013.01);
Abstract

The present disclosure provides detection methods employing HCV core lipid binding domain and DNA binding domain monoclonal antibodies or antibody fragments. In certain embodiments, the lipid binding domain monoclonal antibody or antibody fragment recognizes an epitope in amino acids 141 to 161 of HCV core protein and the DNA binding domain antibody or antibody fragment recognizes an epitope in amino acids 95-123 (e.g., in amino acids 99-117) of HCV core protein.


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