The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2019
Filed:
Mar. 26, 2014
Applicant:
Siemens Healthcare Diagnostics Inc., Tarrytown, NY (US);
Inventor:
Michael Pugia, Granger, IN (US);
Assignee:
SIEMENS HEALTHCARE DIAGNOSTICS, INC., Tarrytown, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); G01N 33/50 (2006.01); G01N 33/569 (2006.01); G01N 33/86 (2006.01); G01N 33/53 (2006.01); C12Q 1/56 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57488 (2013.01); C12Q 1/56 (2013.01); G01N 33/5091 (2013.01); G01N 33/5306 (2013.01); G01N 33/56966 (2013.01); G01N 33/574 (2013.01); G01N 33/86 (2013.01);
Abstract
A ratio of rare cells to non-rare cells in a blood sample suspected of containing rare cells and non-rare cells is enhanced. A treated blood sample is prepared by providing in combination the blood sample, a platelet deactivation agent, a fibrin-formation-arresting agent and fibrin in an amount sufficient to cause a predetermined level of agglutination of the rare cells. The treated blood sample is then contacted with a porous matrix such that agglutinated rare cells are preferentially retained on the porous matrix. The rare cells may then be identified.