The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 15, 2019

Filed:

Jul. 31, 2013
Applicants:

The Regents of the University of California, Oakland, CA (US);

Riken, Saitama, JP;

Inventors:

Hsian-Rong Tseng, Los Angeles, CA (US);

Shuang Hou, Los Angeles, CA (US);

Libo Zhao, Los Angeles, CA (US);

Hsiao-Hua Yu, Saitama, JP;

Shyh-Chyang Luo, Saitama, JP;

Haichao Zhao, Saitama, JP;

Assignees:

The Regents of the University of California, Oakland, CA (US);

Riken, Saitama, JP;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); G01N 25/18 (2006.01); G01N 33/545 (2006.01);
U.S. Cl.
CPC ...
G01N 33/545 (2013.01); G01N 33/54306 (2013.01); G01N 33/54346 (2013.01); G01N 2333/70596 (2013.01);
Abstract

A device for capturing preselected cell types from a fluid sample that includes a plurality of cell types includes a substrate, a plurality of nanowires at least one of attached to or integral with a surface of the substrate such that each nanowire of the plurality of nanowires has an unattached end, and a layer of temperature-responsive material formed on at least the unattached end of each of the plurality of nanowires. The layer of temperature-responsive material has a compact configuration at a first temperature and an expanded configuration at a second temperature so as to facilitate release of cells captured at the first temperature to be released at the second temperature.


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