The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2019
Filed:
Sep. 29, 2015
Applicant:
Expression Pathology, Inc., Rockville, MD (US);
Inventors:
Marlene M. Darfler, Gaithersburg, MD (US);
David B. Krizman, Gaithersburg, MD (US);
Assignee:
EXPRESSION PATHOLOGY, INC., Rockville, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/37 (2006.01); G01N 1/30 (2006.01); G01N 1/40 (2006.01); G01N 1/44 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
G01N 1/4044 (2013.01); C12N 15/1003 (2013.01); C12Q 1/37 (2013.01); G01N 1/44 (2013.01); G01N 1/30 (2013.01);
Abstract
Methods are provided for directly converting histopathologically processed biological samples, tissues, and cells into a multiuse biomolecule lysate. This method allows for simultaneous extraction, isolation, solubilization, and storage of all biomolecules contained within the histopathologically processed biological sample, thereby forming a representative library of said sample. This multi-use biomolecule lysate is dilutable, soluble, capable of being fractionated, and used in biochemical assays.