The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2019
Filed:
Nov. 22, 2016
Applicants:
The Scripps Research Institute, La Jolla, CA (US);
Northwestern University, Evanston, IL (US);
Inventors:
Daniel R. Salomon, San Diego, CA (US);
John Friedewald, Chicago, IL (US);
Sunil Kurian, San Diego, CA (US);
Michael M. Abecassis, Highland Park, IL (US);
Steve Head, Lakeside, CA (US);
Phillip Ordoukhanian, San Diego, CA (US);
Assignee:
The Scripps Research Institute, La Jolla, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6883 (2018.01); G16H 50/30 (2018.01); G16H 50/20 (2018.01); G16B 20/00 (2019.01); G16B 40/30 (2019.01); G16B 40/20 (2019.01); G16B 25/10 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); G16B 20/00 (2019.02); G16B 40/20 (2019.02); G16B 40/30 (2019.02); G16H 50/20 (2018.01); G16H 50/30 (2018.01); C12Q 2537/165 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/158 (2013.01); G16B 25/10 (2019.02); Y02A 90/26 (2018.01);
Abstract
By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified a consensus set of gene expression-based molecular biomarkers associated with subclinical acute rejection (subAR). These genes sets are useful for diagnosis, prognosis, monitoring of subAR.