The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2019
Filed:
Apr. 17, 2015
Anaeropharma Science, Inc., Tokyo, JP;
Koichi Koseki, Tokyo, JP;
Takeshi Masaki, Nagano, JP;
Koichiro Shioya, Nagano, JP;
Hitomi Shimizu, Nagano, JP;
Masao Tsukamoto, Nagano, JP;
Satoshi Kobayashi, Nagano, JP;
Tomio Matsumura, Nagano, JP;
Yuko Shimatani, Nagano, JP;
Anaeropharma Science, Inc., Tokyo, JP;
Abstract
An object is to provide a signal peptide that can secrete a heterologous polypeptide with high efficiency outside the bacterial cell in a bacterium of the genus, an expression cassette that can secrete a heterologous polypeptide with high efficiency outside the bacterial cell, a heterologous polypeptide expression vector, a bacterium of the genuscapable of secreting a heterologous polypeptide. Means for attaining the object is a bacterium of the genustransformed by a vector having an expression cassette sequentially comprising a promoter DNA functioning in a bacterium of the genus, a DNA encoding the secretory signal peptide, a DNA encoding a scFv antibody having an antitumor activity, and a terminator DNA functioning in the bacterium of the genus; and capable of secreting the scFv antibody with high efficiency outside the bacterial cell.