The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 15, 2019

Filed:

Nov. 01, 2017
Applicant:

Dalian Medical University, Dalian, Liaoning, CN;

Inventors:

Jie Zhao, Liaoning, CN;

Shao Li, Liaoning, CN;

Wanqin Zhang, Liaoning, CN;

Assignee:

DALIAN MEDICAL UNIVERSITY, Dalian, Liaoning, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 7/00 (2006.01); A61K 38/17 (2006.01); C07K 14/47 (2006.01); C07K 7/08 (2006.01); A61P 25/16 (2006.01); A61P 25/28 (2006.01); A61P 25/08 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61P 25/08 (2018.01); A61P 25/16 (2018.01); A61P 25/28 (2018.01); A61K 38/00 (2013.01);
Abstract

A scorpion venom heat-resistant synthetic peptide (SVHRSP) contains an amino acid sequence of SEQ ID NO 1. One or more amino acids the amino acid sequence can be substituted or deleted. A pharmaceutical composition that contains the SVHRSP has numerous applications. The pharmaceutical composition can be used to protect neuronal cell against amyloid beta-induced toxic effects, or to inhibit the sodium channel current of a hippocampal neuronal cell, or to protect a neuronal cell against NMDA-induced injury. It may also promotes the formation of a pluripotent neural stem cell from a type II astrocyte, or treats a subject, such as a human, having epilepsy, Alzheimer's disease, or Parkinson's disease.


Find Patent Forward Citations

Loading…