The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 15, 2019

Filed:

Jan. 29, 2019
Applicant:

Rk Pharma Solutions Llc, Piscataway, NJ (US);

Inventors:

Ravishanker Kovi, Monroe, NJ (US);

Jayaraman Kannapan, Gujarat, IN;

Ananda Babu Thirunavakarasu, Gujarat, IN;

Hemant Mande, Gujarat, IN;

Assignee:

RK PHARMA SOLUTIONS LLC, Piscataway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/06 (2006.01);
U.S. Cl.
CPC ...
C07D 487/06 (2013.01); C07B 2200/13 (2013.01);
Abstract

Novel polymorphs of rucaparib camsylate include Form alpha having XRPD peaks at diffraction angles (2θ) of 6.14±0.2, 12.41±0.2, 15.34±0.2, 15.95±0.2, 16.36±0.2, 16.51±0.2 and 19.67±0.2, Form beta having XRPD peaks at diffraction angles (2θ) of 6.86±0.2, 9.58±0.2, 12.75±0.2, 14.56±0.2, 15.05±0.2, 20.76±0.2 and 22.45±0.2, and Form gamma having XRPD peaks at diffraction angles (2θ) of 9.5±0.2, 12.73±0.2, 14.77±0.2, 15.16±0.2, 20.62±0.2, 22.33±0.2, 22.63±0.2 and 27.29±0.2. Methods are disclosed for the preparation of such polymorphic forms and pharmaceutical compositions containing such polymorphic forms. A method is disclosed for preparing a highly pure Form B of rucaparib camsylate. Pharmaceutical compositions containing highly pure Form B prepared by the method are disclosed.


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