The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 15, 2019

Filed:

Sep. 30, 2016
Applicants:

Jiangsu Hengrui Medicine Co., Ltd., Lianyungang, Jiangsu, CN;

Shanghai Hengrui Pharmaceutical Co., Ltd., Shanghai, CN;

Inventors:

Xin Li, Shanghai, CN;

Binqiang Feng, Shanghai, CN;

Yang Chen, Shanghai, CN;

Tao Liu, Shanghai, CN;

Feng He, Shanghai, CN;

Mingxun He, Shanghai, CN;

Weikang Tao, Shanghai, CN;

Piaoyang Sun, Jiangsu, CN;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/352 (2006.01); A61P 25/00 (2006.01); C07D 405/04 (2006.01); C07D 405/14 (2006.01); C07D 409/00 (2006.01); C07D 409/02 (2006.01); C07D 409/14 (2006.01); A61K 31/4436 (2006.01);
U.S. Cl.
CPC ...
C07D 405/04 (2013.01); A61K 31/4436 (2013.01); A61P 25/00 (2018.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01);
Abstract

The present invention relates to an oxa spiro derivative, a preparation method therefor, and applications thereof in medicines. Particularly, the present invention relates to an oxa spiro derivative represented by formula (I), a preparation method therefor, and a pharmaceutical composition comprising the derivative, applications thereof as an MOR receptor agonist, and applications in the preparation of drugs for treating and/or preventing pains and pains-related diseases. Substituent groups in the formula (I) are same as definitions in the specification.


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