The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 15, 2019

Filed:

Nov. 23, 2016
Applicants:

The Texas A&m University System, College Station, TX (US);

The Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Venu G. Varanasi, Dallas, TX (US);

Azhar Ilyas, Arlington, TX (US);

Philip Roger Kramer, Dallas, TX (US);

Taha Azimaie, Dallas, TX (US);

Pranesh B. Aswath, Grapevine, TX (US);

Tugba Cebe, Grapevine, TX (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B33Y 70/00 (2015.01); A61K 38/39 (2006.01); A61K 31/722 (2006.01); A61K 33/00 (2006.01); A61N 5/06 (2006.01); B33Y 10/00 (2015.01); A61K 41/00 (2006.01); B33Y 80/00 (2015.01); B29C 64/106 (2017.01); B29K 67/00 (2006.01);
U.S. Cl.
CPC ...
B33Y 70/00 (2014.12); A61K 31/722 (2013.01); A61K 33/00 (2013.01); A61K 38/39 (2013.01); A61K 41/00 (2013.01); A61N 5/062 (2013.01); B29C 64/106 (2017.08); B33Y 10/00 (2014.12); B33Y 80/00 (2014.12); A61N 2005/0661 (2013.01); B29K 2067/046 (2013.01); B29K 2995/0056 (2013.01);
Abstract

Bio-Inks and methods of using compositions comprising the bio-Inks are disclosed. 3-D tissue repair and regeneration through precise and specific formation of biodegradable tissue scaffolds in a tissue site using the bio-inks are also provided. Specific methylacrylated gelatin hydrogels (MAC) and methacrylated chitosan (MACh) preparations formulated with sucrose, a silicate-containing component (such as laponite), and/or a cross-linking agent (such as a photo-initiator or chemical initiator), as well as powdered preparations of these, are also disclosed. Kits containing these preparations are provided for point-of-care tissue repair in vivo. Superior, more complete (up to 99.85% tissue regeneration within 4 weeks applied in situ), and rapid in situ tissue repair and bone formation are also demonstrated.


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