The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 15, 2019

Filed:

Nov. 26, 2013
Applicant:

The Trustees of Columbia University IN the Ciy of New York, New York, NY (US);

Inventors:

Elisa E. Konofagou, New York, NY (US);

Fabrice Marquet, New York, NY (US);

Yao-Sheng Tung, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 8/08 (2006.01); A61N 7/00 (2006.01); A61B 17/00 (2006.01); A61B 17/22 (2006.01); A61B 90/00 (2016.01); A61B 90/10 (2016.01); A61B 17/225 (2006.01);
U.S. Cl.
CPC ...
A61N 7/00 (2013.01); A61B 8/0808 (2013.01); A61B 8/481 (2013.01); A61B 17/2258 (2013.01); A61B 90/10 (2016.02); A61B 2017/00106 (2013.01); A61B 2017/22008 (2013.01); A61B 2017/22089 (2013.01); A61B 2090/378 (2016.02); A61B 2503/40 (2013.01); A61N 2007/0039 (2013.01);
Abstract

Systems and methods for cavitation-guided opening of a targeted region of tissue within a primate skull are provided. In one example, a method includes delivering one or more microbubbles to proximate the targeted region, applying an ultrasound beam, using a transducer, through the skull of the primate to the targeted region to open the tissue, transcranially acquiring acoustic emissions produced from an interaction between the one or more microbubbles and the tissue, and determining a cavitation spectrum from the acquired acoustic emissions.


Find Patent Forward Citations

Loading…