The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 15, 2019

Filed:

Feb. 16, 2017
Applicants:

Immunolight, Llc, Detroit, MI (US);

Duke University, Durham, NC (US);

Inventors:

Mark Oldham, Durham, NC (US);

Zakaryae Fathi, Raleigh, NC (US);

Wayne F. Beyer, Bahama, NC (US);

Harold Walder, Belville, NC (US);

Frederic A. Bourke, Jr., Greenwich, CT (US);

Mark Dewhirst, Durham, NC (US);

Neil L. Spector, Durham, NC (US);

Paul Yoon, Durham, NC (US);

Justus Adamson, Durham, NC (US);

David Alcorta, Durham, NC (US);

Kim Lyerly, Durham, NC (US);

Leihua Liu, Durham, NC (US);

Takuya Osada, Durham, NC (US);

Assignees:

IMMUNOLIGHT, LLC, Detroit, MI (US);

DUKE UNIVERSITY, Durham, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 5/06 (2006.01); A61K 41/00 (2006.01); A61N 5/10 (2006.01); A61K 31/352 (2006.01);
U.S. Cl.
CPC ...
A61N 5/062 (2013.01); A61K 31/352 (2013.01); A61K 41/0066 (2013.01); A61N 5/10 (2013.01); A61N 2005/0661 (2013.01); A61N 2005/0662 (2013.01); A61N 2005/1089 (2013.01); A61N 2005/1098 (2013.01);
Abstract

A system for treating a diseased site in a human or animal body. The system includes a pharmaceutical carrier including one or more phosphors which are capable of emitting light into the diseased site upon interaction, a photoactivatable drug for intercalating into DNA of cells at the diseased site, one or more devices which infuse the diseased sited with the photoactivatable drug and the pharmaceutical carrier, an x-ray or high energy electron source, and a processor programmed to control a dose of x-rays or electrons to the diseased site for production of light inside the tumor to activate the photoactivatable drug.


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