The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2019
Filed:
Jul. 07, 2017
Glaxosmithkline Biologicals S.a., Rixensart, BE;
Michael T. Kowarik, Zurich, CH;
Michael L. Wetter, Zurich, CH;
Stefan J. Kemmler, Zurich, CH;
Micha A. Häuptle, Zurich, CH;
Veronica Gambillara, Meilen, CH;
Manuela Mally, Watt, CH;
GLAXOSMITHKLINE CIOLOGICALS S.A., Rixensart, BE;
Abstract
Provided herein is a novelO polysaccharide, O25B. Also provided herein are prokaryotic host cells containing enzymes (e.g., glycosyltransferases) used in O25B production. The host cells provided herein produce O25B bioconjugates, wherein said bioconjugates contain O25B linked to a carrier protein. Further provided herein are compositions, e.g., pharmaceutical compositions, including O25B and/or bioconjugates containing O25B. Such compositions can be used as vaccines against infection with ExPEC, and may further include one or more additional bioconjugates.