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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10441602 B1

PDFFull Text
Date of Patent:
Oct. 15, 2019

Filed:

Oct. 07, 2016

Human gastrointestinal microbiome modulating composition and methods of use

Applicant:

Microbiome Therapeutics Llc, Broomfield, CO (US);

Inventors:

Mark L. Heiman, Indianapolis, IN (US);

Dean P. Stull, Longmont, CO (US);

Justin W. Peno, Saint Francisville, LA (US);

Assignee:

MicroBiome Therapeutics, LLC, Broomfield, CO (US);

Attorney:

Cooley LLP

Primary Examiner:

Michael V Meller

Int. Cl.
CPC ...
A61K 36/00 (2006.01); A61K 31/733 (2006.01); A61K 31/047 (2006.01); A61K 31/716 (2006.01); A61K 31/718 (2006.01); A61K 36/45 (2006.01); A61K 9/00 (2006.01); A61K 31/155 (2006.01); A61K 38/28 (2006.01); A23L 29/212 (2016.01); A23L 33/00 (2016.01); A23L 33/105 (2016.01); A23L 33/21 (2016.01); A61K 31/05 (2006.01); A61K 36/88 (2006.01); A61K 36/899 (2006.01); A61K 9/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/733 (2013.01); A23L 29/212 (2016.08); A23L 33/00 (2016.08); A23L 33/105 (2016.08); A23L 33/21 (2016.08); A23L 33/30 (2016.08); A61K 9/0095 (2013.01); A61K 31/047 (2013.01); A61K 31/05 (2013.01); A61K 31/155 (2013.01); A61K 31/716 (2013.01); A61K 31/718 (2013.01); A61K 36/00 (2013.01); A61K 36/45 (2013.01); A61K 36/88 (2013.01); A61K 36/899 (2013.01); A61K 38/28 (2013.01); A23V 2002/00 (2013.01); A61K 9/0031 (2013.01); A61K 9/10 (2013.01);
Abstract

A formulation to increase the ratio of gastrointestinal microbiota in phylum Bacteroidetes to microbiota of Firmicutes phylum preferably includes about 20-60 mg/kg of body weight of fermentable fiber, about 10-30 mg/kg of body weight of beta glucan and about 20-60 mg/kg of body weight of blueberry extracts or any fruit or berry ingredient preparation containing similar phenolics. This formulation is preferably used to control body weight, body composition, and blood glucose regulation, preferably in humans, and is preferably administered orally, preferably twice per day.

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