The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2019

Filed:

Aug. 05, 2013
Applicant:

University of Virginia Patent Foundation, Charlottesville, VA (US);

Inventors:

Edward A. Ortiz, Charlottesville, VA (US);

Stephen D. Patek, Charlottesville, VA (US);

Marc D. Breton, Charlottesville, VA (US);

Leon S. Farhi, Charlottesville, VA (US);

Boris P. Kovatchev, Charlottesville, VA (US);

Assignee:

University of Virginia Patent Foundation, Charlottesville, VA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); G16H 50/50 (2018.01); C12Q 1/54 (2006.01);
U.S. Cl.
CPC ...
G16H 50/50 (2018.01); C12Q 1/54 (2013.01);
Abstract

Time-varying hyperglycemic stresses are derived from actual ICU patients and applied to non-critically ill virtual patients, using any model of normal glucose-insulin physiology that fulfills certain requirements, in order to model and simulate stress hyperglycemia. Other aspects provide: 1) a methodology to perform sensitivity analyses of the parameters of ICU insulin infusion therapy protocols and to improve the protocols; and 2) a training system for clinicians about the course and management of stress hyperglycemia in the ICU or other facility.


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