The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2019
Filed:
Dec. 20, 2018
Applicant:
Icahn School of Medicine AT Mount Sinai, New York, NY (US);
Inventors:
Andrea Branch, New York, NY (US);
Francis Eng, New York, NY (US);
Assignee:
Icahn School of Medicine at Mount Sinai, New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); A61K 39/00 (2006.01); G01N 21/00 (2006.01); G01N 21/64 (2006.01); G01N 33/68 (2006.01); G01N 33/576 (2006.01); C07K 16/10 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5767 (2013.01); C07K 16/109 (2013.01); C07K 2317/34 (2013.01); C07K 2317/565 (2013.01); G01N 2333/186 (2013.01);
Abstract
The present disclosure relates to hepatitis C virus (HCV) core and minicore-binding molecules and nucleic acid sequences encoding such molecules. In particular embodiments, the present invention provides HCV core and minicore-binding molecules (e.g., monoclonal antibodies or antibody fragments) with particular light chain and/or heavy chain CDRs (e.g., selected from SEQ ID NOS: 2-4 and 6-8) and methods for using such molecules to detect the presence of HCV core proteins (e.g., mature p21 core protein or minicore proteins) in a sample.