The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2019

Filed:

Sep. 19, 2016
Applicant:

Agilent Technologies, Inc., Santa Clara, CA (US);

Inventors:

Bruce Richter, Wilmington, DE (US);

Derick Lucas, Wilmington, DE (US);

David Long, Glen Mills, PA (US);

Limian Zhao, West Chester, PA (US);

Assignee:

AGILENT TECHNOLOGIES, INC., Santa Clara, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 1/00 (2006.01); G01N 1/40 (2006.01); B01D 15/38 (2006.01); B01J 20/22 (2006.01); B01J 20/28 (2006.01); B01J 20/289 (2006.01); G01N 30/72 (2006.01); G01N 30/84 (2006.01);
U.S. Cl.
CPC ...
G01N 1/405 (2013.01); B01D 15/3823 (2013.01); B01J 20/22 (2013.01); B01J 20/289 (2013.01); B01J 20/28016 (2013.01); G01N 30/72 (2013.01); G01N 30/84 (2013.01); B01J 2220/46 (2013.01); B01J 2220/54 (2013.01); G01N 2030/8435 (2013.01);
Abstract

Aspects of the present disclosure include a solid phase sorbent for preparation of analytical samples. The solid phase sorbent includes particles that are surface modified with an α-cyclodextrin moiety. Also provided is a method of reducing matrix effects in an analytical sample. In some embodiments, the method includes contacting a sample comprising a matrix-interfering agent and an analyte with α-cyclodextrin modified particles to produce a contacted sample wherein the matrix-interfering agent binds to the α-cyclodextrin modified particles; separating the α-cyclodextrin modified particles from the contacted sample to produce a matrix-reduced composition; and detecting the analyte in the matrix-reduced composition. Systems for practicing the subject methods are provided that include the subject solid phase sorbent.


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