The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2019

Filed:

Mar. 13, 2014
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Jonathan Schneck, Baltimore, MD (US);

Mathias Oelke, Baltimore, MD (US);

Karlo Perica, Baltimore, MD (US);

Assignee:

THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/44 (2006.01); C12N 5/0781 (2010.01); C12N 5/0783 (2010.01); A61K 39/39 (2006.01); A61K 47/68 (2017.01); A61K 47/69 (2017.01); A61K 35/17 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0635 (2013.01); A61K 39/0011 (2013.01); A61K 39/39 (2013.01); A61K 39/44 (2013.01); A61K 47/6849 (2017.08); A61K 47/6939 (2017.08); C12N 5/0636 (2013.01); A61K 35/17 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/572 (2013.01); A61K 2039/60 (2013.01); A61K 2039/605 (2013.01); A61K 2039/6087 (2013.01); A61K 2039/625 (2013.01); A61K 2039/64 (2013.01); C12N 2501/50 (2013.01); C12N 2501/51 (2013.01); C12N 2529/00 (2013.01); C12N 2533/10 (2013.01); C12N 2533/70 (2013.01);
Abstract

This disclosure provides nano-scale Artificial Antigen Presenting Cells (aAPC), which deliver stimulatory signals to lymphocytes, including cytotoxic lymphocytes, for use as a powerful tool for immunotherapy.


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