The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2019

Filed:

Oct. 27, 2016
Applicant:

Fidia Farmaceutici S.p.a., Abano Terme, IT;

Inventors:

Matteo D'Este, Abano Terme, IT;

Giovanni Gennari, Abano Terme, IT;

Assignee:

FIDIA FARMACEUTICI S.P.A., Abano Terme, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08B 37/00 (2006.01); A61K 31/136 (2006.01); A61K 31/737 (2006.01); A61K 45/06 (2006.01); A61K 8/73 (2006.01); A61K 9/00 (2006.01); A61K 38/47 (2006.01); A61Q 1/06 (2006.01); A61Q 11/00 (2006.01);
U.S. Cl.
CPC ...
C08B 37/00 (2013.01); A61K 8/735 (2013.01); A61K 9/007 (2013.01); A61K 9/0014 (2013.01); A61K 31/136 (2013.01); A61K 31/737 (2013.01); A61K 38/47 (2013.01); A61K 45/06 (2013.01); A61Q 1/06 (2013.01); A61Q 11/00 (2013.01); C12Y 302/01035 (2013.01);
Abstract

The object of the present invention relates to the new and surprising use of sulfated hyaluronic acid (HAS) as regulator agent of the cytokine activity (pro- and anti-inflammatory) and consequently the use of HAS for the preparation of a new medicine for topic use in the prevention and treatment of pathologies associated with the activation and/or deficiency of cytokines of a pro- and anti-inflammatory nature. The Applicant has in fact discovered the exclusive capacity of HAS in modulating the activity of these particular proteins, it has studied the action mechanism and demonstrated the substantial difference between the different sulfated types known in the state of the art, but above all it has demonstrated an unexpectedly high activity of HAS vs different types and strains of Herpes virus, Cytomegalovirus and the virus of vesicular stomatitis. Finally, a further object of the present invention is the use of HAS as a skin absorption promoter of drugs of an anti-inflammatory nature.


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