The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2019
Filed:
May. 10, 2015
Applicant:
Sorrento Therapeutics, Inc., San Diego, CA (US);
Inventors:
Yanwen Fu, San Diego, CA (US);
Gunnar F. Kaufmann, San Diego, CA (US);
Bryan Jones, San Diego, CA (US);
Raheleh Toughiri, San Diego, CA (US);
Assignee:
Sorrento Therapeutics, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/46 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01);
U.S. Cl.
CPC ...
C07K 16/468 (2013.01); C07K 16/2827 (2013.01); C07K 16/2863 (2013.01); C07K 16/30 (2013.01); C07K 16/3015 (2013.01); C07K 2317/31 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/53 (2013.01); C07K 2317/54 (2013.01); C07K 2317/55 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract
There is disclosed a process for forming chemically-locked bispecific or heterodimer antibodies, preferably in the IgG class, in high specificity and with high homogeneity. More specifically, there is disclosed a chemically-locked bispecific IgG class antibody having a linkage region joined together with bio-orthogonal click chemistry.