The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2019
Filed:
Mar. 04, 2011
Applicants:
Taichi Kuramochi, Shizuoka, JP;
Tomoyuki Igawa, Shizuoka, JP;
Atsuhiko Maeda, Shizuoka, JP;
Futa Mimoto, Shizuoka, JP;
Inventors:
Taichi Kuramochi, Shizuoka, JP;
Tomoyuki Igawa, Shizuoka, JP;
Atsuhiko Maeda, Shizuoka, JP;
Futa Mimoto, Shizuoka, JP;
Assignee:
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); C07K 16/28 (2006.01); C07K 16/18 (2006.01); C07K 19/00 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/00 (2013.01); C07K 2317/522 (2013.01); C07K 2317/524 (2013.01); C07K 2317/71 (2013.01); C07K 2317/72 (2013.01);
Abstract
The present inventors carried out dedicated research to generate antibody constant regions with reduced Fcγ receptor-binding activity by altering amino acid sequences in the antibody constant region. As a result, the present inventors successfully identified novel constant region sequences with reduced Fcγ receptor-binding activity compared to conventional antibody constant regions.