The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2019
Filed:
Jun. 26, 2015
Applicant:
Stealthyx Therapeutics Limited, Cambridge, GB;
Inventors:
Yuti Chernajovsky, London, GB;
Lisa Mullen, London, GB;
Gillian Adams, London, GB;
David James Gould, London, GB;
Hawzheen Muhammad, London, GB;
Assignee:
Stealthyx Therapeutics Limited, Cambridge, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/495 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 14/495 (2013.01); C07K 16/2863 (2013.01); C07K 2319/02 (2013.01); C07K 2319/30 (2013.01); C07K 2319/50 (2013.01); C07K 2319/73 (2013.01);
Abstract
The present invention provides a fusion protein comprising a latency associated peptide (LAP), a pharmaceutically active agent and an amino acid sequence comprising a dimerization domain, wherein the LAP and the pharmaceutically active agent are connected by an amino acid sequence comprising a proteolytic cleavage site. Also provided are nucleic acids enclosing such fusion proteins, process for their preparation, pharmaceutical compositions, kits and uses thereof in medicine.