The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2019
Filed:
Aug. 21, 2017
Applicant:
Sage Therapeutics, Inc., Cambridge, MA (US);
Inventors:
Ravindra B. Upasani, San Jose, CA (US);
Benny C. Askew, Marshfield, MA (US);
Boyd L. Harrison, Princeton Junction, NJ (US);
Francesco G. Salituro, Marlborough, MA (US);
Albert J. Robichaud, Cambridge, MA (US);
Assignee:
Sage Therapeutics, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07J 5/00 (2006.01); C07J 7/00 (2006.01); C07J 43/00 (2006.01); C07J 31/00 (2006.01); C07J 9/00 (2006.01);
U.S. Cl.
CPC ...
C07J 43/003 (2013.01); C07J 5/0015 (2013.01); C07J 7/002 (2013.01); C07J 7/008 (2013.01); C07J 7/0085 (2013.01); C07J 9/005 (2013.01); C07J 31/006 (2013.01);
Abstract
Provided herein are 3,3-disubstituted 19-nor-steroidal compounds according to Formula (I) and (III): where R, R, R, R, R, R, R, R, and Rare as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, insomnia, anxiety, depression, traumatic brain injury (TBI), stress, and epilepsy.