The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2019

Filed:

Jul. 31, 2014
Applicants:

Ionis Pharmaceuticals, Inc., Carlsbad, CA (US);

Board of Regents of the University of Texas System, Austin, TX (US);

Inventors:

Thazha P. Prakash, Carlsbad, CA (US);

Jiaxin Hu, Coppell, TX (US);

Jing Liu, Austin, TX (US);

Dongbo Yu, Austin, TX (US);

David Corey, Dallas, TX (US);

Eric E. Swayze, Encinitas, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C07H 21/02 (2006.01);
U.S. Cl.
CPC ...
C07H 21/02 (2013.01); C12N 15/113 (2013.01); C12N 2310/11 (2013.01); C12N 2310/32 (2013.01); C12N 2320/34 (2013.01);
Abstract

Described are compounds and methods useful for the treatment and investigation of diseases and disorders associated with expanded repeat-containing RNA molecules. In certain embodiments, compounds and methods useful for the modulation of ATXN-3 pre-mRNA are described. In certain embodiments, compounds and methods useful for the modulation of ATN-1 mRNA are described.


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