The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2019

Filed:

Jun. 06, 2016
Applicant:

Bayer Pharma Aktiengesellschaft, Berlin, DE;

Inventors:

Henrik Teller, Schwaan, DE;

Alexander Straub, Wuppertal, DE;

Markus Brechmann, San Francisco, CA (US);

Thomas Müller, Langenfeld, DE;

Mark Meininghaus, Wuppertal, DE;

Katrin Nowak-Reppel, Berlin, DE;

Hanna Tinel, Wuppertal, DE;

Klaus Münter, Wülfrath, DE;

Daniela Fliegner, Berlin, DE;

Thomas Mondritzki, Velbert, DE;

Melissa Boultadakis Arapinis, Düsseldorf, DE;

Tobias Marquardt, Wuppertal, DE;

Alexandros Vakalopoulos, Hilden, DE;

Anne-Sophie Rebstock, Champagne au Mont d'Or, FR;

Matthias Beat Wittwer, Riehen, CH;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61P 9/04 (2006.01); A61K 31/4375 (2006.01); A61K 31/4545 (2006.01); A61K 31/496 (2006.01); A61K 31/513 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/4375 (2013.01); A61K 31/4545 (2013.01); A61K 31/496 (2013.01); A61K 31/513 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); A61P 9/04 (2018.01); C07D 519/00 (2013.01);
Abstract

The present application relates to positive allosteric modulators of the muscarinic M2 receptor, especially to novel 7-substituted 1-arylnaphthyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, in particular for treatment and/or prevention of cardiovascular disorders and/or renal disorders.


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