The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2019

Filed:

Aug. 20, 2018
Applicant:

Taizhou Danding Biotechnology Co., Ltd., Taizhou, Jiangsu, CN;

Inventors:

Zhengbing Gu, Jiangsu, CN;

Jie Zhang, Jiangsu, CN;

Yuehong Tao, Jiangsu, CN;

Cheng Zeng, Jiangsu, CN;

Lili Xu, Jiangsu, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 311/30 (2006.01); A61K 31/352 (2006.01); A61K 36/41 (2006.01);
U.S. Cl.
CPC ...
C07D 311/30 (2013.01); A61K 31/352 (2013.01); A61K 36/41 (2013.01); A61K 2236/00 (2013.01);
Abstract

A method for extracting herbacetin from plants ofL., comprising the following steps: 1) performing an extracting process for the pulverized medicalL. with an extracting solvent, and condensing to obtain an extract; 2) performing a leaching process for the extract and performing an acid hydrolysis for the extracted aqueous layer; 3) performing a leaching process for the solution after the acid hydrolysis with an organic solvent, combining the organic layer and concentrating under reduced pressure to obtain a herbacetin extract; 4) treating the herbacetin extract through polyamide column chromatography, collecting the outflow containing herbacetin and drying through condensation to obtain a crude herbacetin product; 5) treating the crude herbacetin product through reverse-phase silica-gel column chromatography, collecting the outflow containing herbacetin, drying through condensation and recrystallizing to obtain a pure herbacetin product. The invention for herbacetin preparation is characterized by simple process, high yield.


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