The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2019
Filed:
Mar. 29, 2016
Northwestern University, Evanston, IL (US);
Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL (US);
University of Maryland, Baltimore, Baltimore, MD (US);
Dean Ho, Los Angeles, CA (US);
Erik M. Robinson, Chicago, IL (US);
Sunjay Kaushal, Pikesville, MD (US);
Patrick M. McCarthy, Winnetka, IL (US);
Northwestern University, Evanston, IL (US);
University of Maryland, Baltimore, MD (US);
Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL (US);
Abstract
The present invention provides single sheet and compound para-xylene films for therapeutic uses. For example, the present invention provides single sheet para-xylene films useful as tissue separators and/or adhesion barriers in a subject, where the top and/or bottom surfaces of such films have a water contact angle between 75 and 95 degrees (e.g., to prevent adhesion formation). The present invention also provides compound films composed of at least two para-xylene polymer films with a therapeutic molecule layer in between. Such compound films, when used in vivo (e.g., as a tissue separator and to treat inflammation or atrial fibrillation) allow either therapeutic molecule elution through one of the para-xylene layers, or therapeutic molecule release when the compound film is pierced, such as when it is sutured in place.