The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2019

Filed:

Jun. 26, 2014
Applicant:

Regentis Biomaterials Ltd., Or-Akiva, IL;

Inventors:

Yonatan Shachaf, Haifa, IL;

Aharon Wechsler, Shoham, IL;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 27/26 (2006.01); A61L 27/52 (2006.01); A61L 27/58 (2006.01); A61L 27/18 (2006.01); A61L 27/22 (2006.01);
U.S. Cl.
CPC ...
A61L 27/26 (2013.01); A61L 27/18 (2013.01); A61L 27/225 (2013.01); A61L 27/52 (2013.01); A61L 27/58 (2013.01); A61L 2430/06 (2013.01);
Abstract

A pharmaceutical, cosmetic or cosmeceutical composition which exhibits a reverse thermal gelation is disclosed herein, as well as a composition-of-matter comprising a cross-linked form of the composition, and a process for producing the composition-of-matter. The composition is characterized as exhibiting a shear storage modulus of at least 100 Pa at temperatures in a range of from 17° C. to 21° C., and a shear storage modulus of less than 100 Pa at a temperature of 4° C., and as being curable in a physiological medium, and/or comprises a polymer-polypeptide conjugate comprising a polypeptide having attached thereto at least two polymeric moieties, wherein at least one of said polymeric moieties further comprises at least one polymerizable group; a poloxamer; and a poloxamer substituted by at least one polymerizable group. Further disclosed herein are uses of the composition and/or composition-of-matter in the treatment of tissue damage or loss.


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