The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2019

Filed:

May. 26, 2016
Applicant:

Kirin Kabushiki Kaisha, Tokyo, JP;

Inventors:

Yasuhisa Ano, Tokyo, JP;

Masahiro Kita, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/05 (2006.01); A23L 33/18 (2016.01); A61P 25/28 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/05 (2013.01); A23L 33/18 (2016.08); A61P 25/28 (2018.01); A61P 29/00 (2018.01);
Abstract

An oligopeptide having a good anti-inflammation effect on microglia has been found, and based on this finding, a composition to be used for suppressing the inflammation of microglia is provided. Inflammation suppression action of a dipeptide has been comprehensively analyzed using the proinflammatory cytokine production of microglia as an indicator. As a result, it has been revealed that an oligopeptide including the sequence LH, DV or MH has a good inflammation suppression effect. The composition containing any of these oligopeptides can provide a composition having the effect of suppressing the excessive inflammatory action of microglia.


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