The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2019

Filed:

Dec. 21, 2015
Applicant:

Cellics Therapeutics, Inc., San Diego, CA (US);

Inventor:

Tien-Li Lee, San Diego, CA (US);

Assignee:

Cellics Therapeutics, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/18 (2015.01); A61K 9/00 (2006.01); A61K 9/51 (2006.01); A61K 45/06 (2006.01); A61K 35/14 (2015.01); G01N 33/80 (2006.01); A61M 1/02 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5176 (2013.01); A61K 9/0019 (2013.01); A61K 9/0026 (2013.01); A61K 35/14 (2013.01); A61K 35/18 (2013.01); A61K 45/06 (2013.01); G01N 33/80 (2013.01); A61M 1/02 (2013.01);
Abstract

The present invention relates to methods, combinations and pharmaceutical compositions for supplying a blood source from a donor source with a mis-matched blood type, or potentially a mis-matched blood type, to a recipient, using, inter alia, an effective amount of a nanoparticle comprising a) an inner core comprising a non-cellular material, and b) an outer surface comprising a cellular membrane derived from a red blood cell, the cellular membrane of the nanoparticle comprising a blood type antigen that exists on the red blood cell from the donor source, but is missing or potentially missing on red blood cells of the recipient.


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