The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2019

Filed:

Mar. 25, 2015
Applicants:

Ethicon, Inc., Somerville, NJ (US);

Omrix Biopharmaceuticals Ltd., Rehovot, IL;

Inventors:

Ashley DeAnglis, Skillman, NJ (US);

Yair Pilpel, Rehovot, IL;

Yuri Zherdev, Rehovot, IL;

Sivan Doron, Moshav Arugot, IL;

Lior Erez, Rehovot, IL;

Assignees:

Ethicon, Inc., Somerville, NJ (US);

Omrix Biopharmaceuticals Ltd., Rehovot, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 5/178 (2006.01); A61L 15/32 (2006.01); A61L 24/10 (2006.01); A61K 38/36 (2006.01); A61K 38/48 (2006.01); A61B 17/00 (2006.01); A61M 3/00 (2006.01);
U.S. Cl.
CPC ...
A61B 17/00491 (2013.01); A61K 38/36 (2013.01); A61K 38/363 (2013.01); A61K 38/4833 (2013.01); A61L 24/106 (2013.01); A61M 3/005 (2013.01); A61M 2202/045 (2013.01); C12Y 304/21005 (2013.01);
Abstract

Provided herein are systems for preparing and delivering fibrin sealant to a surface and methods of use thereof. In one embodiment, the system comprises: a. a quantity of a liquid mixture disposed within a container, the mixture comprising: I. fibrin or II. fibrinogen and Factor II; and b. a resin bed disposed within a vessel, the vessel capable of being in fluid communication with the container, wherein when in fluid communication, passage of the mixture through the vessel results in modification of the concentration of small molecules inhibitor(s) and/or inducer(s) within the mixture, favoring fibrin clot formation.


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