The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10429391 B1

PDF
Full Text
Expired
Date of Patent:
Oct. 01, 2019

Filed:

Sep. 08, 2014
Applicant:

Leibniz-institut Für Analytische Wissenschaften—isas—e.v., Dortmund, DE;

Inventors:

Barbara Sitek, Witten, DE;

Helmut E. Meyer, Recklinghausen, DE;

Dominik Megger, Dortmund, DE;

Thilo Bracht, Bochum, DE;

Juliet Padden, Bochum, DE;

Hideo A. Baba, Essen, DE;

Jörg F. Schlaak, Essen, DE;

Frank Weber, Essen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 31/00 (2006.01); G01N 33/574 (2006.01); G01N 33/68 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57446 (2013.01); G01N 33/57438 (2013.01); G01N 33/6848 (2013.01); G01N 2500/04 (2013.01); G01N 2560/00 (2013.01); G01N 2570/00 (2013.01); G01N 2800/52 (2013.01);
Abstract

The invention relates to a method for identifying specific marker proteins (biomarkers) for cholangiocellular carcinoma (CCC), the biomarkers for CCC identified by the method and the use thereof, in particular for diagnosis, surveillance and treatment. The invention further relates to a diagnostic device comprising the biomarkers for CCC and a screening assay wherein these biomarkers for CCC are used to identify novel pharmaceutical compounds for treatment of CCC.


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