The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10429328 B1

PDF
Full Text
Expired
Date of Patent:
Oct. 01, 2019

Filed:

Jan. 23, 2015
Applicant:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

Inventors:

Qiao Lin, New York, NY (US);

Bin Wang, New York, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01K 17/00 (2006.01); G01N 25/48 (2006.01); B01L 3/00 (2006.01); B01L 7/00 (2006.01);
U.S. Cl.
CPC ...
G01N 25/482 (2013.01); B01L 3/502715 (2013.01); B01L 7/00 (2013.01); G01K 17/00 (2013.01); G01N 25/4893 (2013.01); B01L 2200/027 (2013.01); B01L 2200/14 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0877 (2013.01); B01L 2300/0883 (2013.01); B01L 2300/1827 (2013.01);
Abstract

A microelectromechanical systems-based calorimetric device includes first and second micromixers and first and second thermally-isolated microchambers. A first solution including a sample and a reagent is introduced to the first microchamber via the first micromixer, and a second solution including a sample and a buffer is introduced to the second microchamber via the second micromixer. A thermopile measures the differential temperature between the first microchamber and the second microchamber and outputs a voltage representative of the difference. The output voltage can be used to calculate reaction parameters.


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