The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2019

Filed:

Mar. 27, 2015
Applicant:

Kabushiki Kaisha Dnaform, Yokohama-shi, Kanagawa, JP;

Inventors:

Takeshi Hanami, Saitama, JP;

Yoshihide Hayashizaki, Saitama, JP;

Takahiro Soma, Saitama, JP;

Yasumasa Kimura, Kanagawa, JP;

Assignee:

KABUSHIKI KAISHA DNAFORM, Kanagawa, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6818 (2018.01); C12Q 1/6816 (2018.01); C09B 23/04 (2006.01); C09B 23/06 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6818 (2013.01); C09B 23/04 (2013.01); C09B 23/06 (2013.01); C12Q 1/6816 (2013.01);
Abstract

The present invention is intended to provide a novel fluorescent labeled single-stranded nucleic acid, by which the background of an exciton oligomer can be further reduced and the novel use thereof. The present invention relates to a labeled single-stranded nucleic acid having at least two fluorescent atomic group pairs that exhibit an exciton effect. The labeled single-stranded nucleic acid is characterized in that the emission peak wavelength of one of the fluorescent atomic group pairs (fluorescent atomic group pair A) is shorter than the excitation peak wavelength of the other fluorescent atomic group pair (fluorescent atomic group pair B), and the fluorescent atomic group pairs A and B have a Förster resonance energy transfer (FRET) effect. This fluorescent labeled single-stranded nucleic acid is usable as a primer for amplifying a target nucleic acid or a probe to be hybridized with a target nucleic acid.


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