The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2019
Filed:
Oct. 17, 2017
Applicant:
Apse, Inc., St. Louis, MO (US);
Inventors:
Juan Pedro Humberto Arhancet, St. Louis, MO (US);
Juan P. Arhancet, St. Louis, MO (US);
Kimberly Delaney, St. Louis, MO (US);
Kathleen B. Hall, St. Louis, MO (US);
Neena Summers, St. Louis, MO (US);
Edward Oates, St. Louis, MO (US);
Assignee:
APSE, INC., St. Louis, MO (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 48/00 (2006.01); C12N 15/11 (2006.01); C07K 14/005 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 9/5184 (2013.01); A61K 48/00 (2013.01); C07K 14/005 (2013.01); C12N 15/111 (2013.01); C12N 2310/12 (2013.01); C12N 2310/121 (2013.01); C12N 2310/14 (2013.01); C12N 2310/141 (2013.01); C12N 2310/3519 (2013.01); C12N 2310/531 (2013.01); C12N 2320/32 (2013.01); C12N 2330/50 (2013.01); C12N 2795/00023 (2013.01); C12N 2795/00042 (2013.01); C12N 2795/18122 (2013.01); C12N 2795/18123 (2013.01); C12N 2795/18142 (2013.01);
Abstract
Novel processes and compositions are described which use viral capsid proteins resistant to hydrolases to prepare virus-like particles to enclose and subsequently isolate and purify target cargo molecules of interest including nucleic acids such as siRNAs and shRNAs, miRNAs, messenger RNAs, small peptides and bioactive molecules.