The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2019
Filed:
Sep. 30, 2016
Applicants:
Sichuan University, Chengdu, Sichuan, CN;
Yaopharma Co., Ltd., Chongqing, CN;
Inventors:
Zhirong Zhang, Sichuan, CN;
Tao Gong, Sichuan, CN;
Yan Zhang, Chongqing, CN;
Xu Song, Sichuan, CN;
Tijia Chen, Sichuan, CN;
Yao Fu, Sichuan, CN;
Xun Sun, Sichuan, CN;
Xiaoqing Bai, Chongqing, CN;
Bei Zhang, Chongqing, CN;
Assignees:
SICHUAN UNIVERSITY, Chengdu, Sichuan, CN;
YAOPHARMA CO., LTD., Chongqing, CN;
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/50 (2006.01); A61K 47/42 (2017.01); A61K 47/64 (2017.01); A61K 38/12 (2006.01); A61K 35/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/50 (2013.01); A61K 38/12 (2013.01); A61K 47/42 (2013.01); A61K 47/64 (2017.08); A61P 35/00 (2018.01);
Abstract
Provided is a nRGD polypeptide formed by connecting alanine-alanine-asparagine (AAN) and a polypeptide containing arginine-glycine-aspartic acid (RGD), wherein the nRGD polypeptide can target tumor vessels, tumor cells and tumor-associated macrophages, and mediate the targeted delivery of tumors.