The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2019

Filed:

Sep. 27, 2018
Applicant:

Glaxosmithkline Intellectual Property Development Limited, Brentford, Middlesex, GB;

Inventors:

Zehong Wan, Shanghai, CN;

Xiaomin Zhang, Shanghai, CN;

Jian Wang, Shanghai, CN;

Matthew Robert Sender, Collegeville, PA (US);

Eric Steven Manas, Collegeville, PA (US);

Raphael Anthony Rivero, Collegeville, PA (US);

Joseph E Pero, Collegeville, PA (US);

Christopher Ernst Neipp, Collegeville, PA (US);

Vipulkumar Kantibhai Patel, Stevenage, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/14 (2006.01); C07D 491/20 (2006.01); C07D 471/14 (2006.01); C07D 471/20 (2006.01); C07D 487/04 (2006.01); C07D 498/14 (2006.01); A61K 31/527 (2006.01); A61K 31/519 (2006.01); C07D 513/14 (2006.01);
U.S. Cl.
CPC ...
C07D 487/14 (2013.01); C07D 471/14 (2013.01); C07D 471/20 (2013.01); C07D 487/04 (2013.01); C07D 491/20 (2013.01); C07D 498/14 (2013.01); C07D 513/14 (2013.01); H05K 999/99 (2013.01);
Abstract

The present invention relates to novel compounds that inhibit Lp-PLAactivity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA, for example Alzheimer's disease.


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