The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2019

Filed:

Aug. 10, 2016
Applicant:

Forum Pharmaceuticals, Inc., Waltham, MA (US);

Inventors:

Raksha Acharya, Bedford, MA (US);

Duane A. Burnett, Wayland, MA (US);

Matthew Gregory Bursavich, Needham, MA (US);

Andrew Simon Cook, Stow, MA (US);

Bryce Alden Harrison, Framingham, MA (US);

Andrew J. McRiner, Melrose, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 453/02 (2006.01); C07D 453/00 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
C07D 453/02 (2013.01); C07D 453/00 (2013.01); A61P 25/00 (2018.01);
Abstract

The present invention relates to novel geminal substituted aminobenzisoxazole compounds, and pharmaceutical compositions of the same, that are suitable as agonists or partial agonists of α7-nAChR, and methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering the compound or composition to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.


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