The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2019
Filed:
Feb. 12, 2019
Applicant:
Silverback Therapeutics, Inc., Seattle, WA (US);
Inventors:
Craig Alan Coburn, Seattle, WA (US);
Peter Robert Baum, Seattle, WA (US);
Sean Wesley Smith, Seattle, WA (US);
Assignee:
Silverback Therapeutics, Inc., Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 223/16 (2006.01); A61K 31/55 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); A61K 47/68 (2017.01); C07D 471/04 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61K 31/55 (2013.01); A61K 47/6803 (2017.08); A61P 35/00 (2018.01); C07D 223/16 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 471/04 (2013.01);
Abstract
Benzazepine compounds, conjugates, and pharmaceutical compositions for use in the treatment of disease, such as cancer, are disclosed herein. The disclosed benzazepine compounds are useful, among other things, in the treating of cancer and modulating TLR8. Additionally, benzazepine compounds incorporated into a conjugate with an antibody construct are described herein.