The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2019
Filed:
Feb. 14, 2018
Applicant:
Piramal Enterprises Limited, Mumbai, IN;
Inventors:
Assignee:
Piramal Enterprises Limited, Mumbai, IN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 295/096 (2006.01); C07B 43/04 (2006.01); C07C 211/46 (2006.01);
U.S. Cl.
CPC ...
C07D 295/096 (2013.01); C07B 43/04 (2013.01); C07C 211/46 (2013.01);
Abstract
The present invention provides an improved process for preparation of 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]-piperazine; commonly known as vortioxetine (referred to as the compound (I)) and pharmaceutically acceptable salts thereof; wherein the process comprises reaction of 2-((2,4-dimethylphenyl)thio)aniline (II) with bis(2-alkyl)amine (IIIa) or its salt in the presence of a cyclic amide solvent.