The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2019

Filed:

Feb. 22, 2018
Applicants:

Abbvie S.à.r.l., Luxembourg, LU;

Galapagos NV, Mechelen, BE;

Inventors:

Robert J. Altenbach, Chicago, IL (US);

Andrew Bogdan, Evanston, IL (US);

Nicolas Desroy, Romainville, FR;

Gregory A. Gfesser, Lindenhurst, IL (US);

Stephen N. Greszler, Vernon Hills, IL (US);

Philip R. Kym, Libertyville, IL (US);

Bo Liu, Waukegan, IL (US);

Karine Fabienne Malagu, Saffron, GB;

Nuria Merayo Merayo, Romainville, FR;

Mathieu Rafaël Pizzonero, Romainville, FR;

Xenia B. Searle, Grayslake, IL (US);

Steven Emiel Van der Plas, Mechelen, BE;

Xueqing Wang, Northbrook, IL (US);

Ming C. Yeung, Grayslake, IL (US);

Gang Zhao, Northbrook, IL (US);

Assignees:

AbbVie S.á.r.l., Luxembourg, LU;

Galapagos NV, Mechelen, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/12 (2006.01); C07C 311/51 (2006.01); A61P 11/00 (2006.01); C07D 215/48 (2006.01); C07D 307/81 (2006.01); C07D 311/04 (2006.01); C07D 311/76 (2006.01); C07D 317/68 (2006.01); C07D 319/22 (2006.01); C07C 317/14 (2006.01); C07D 407/12 (2006.01); C07D 307/16 (2006.01);
U.S. Cl.
CPC ...
C07C 311/51 (2013.01); A61P 11/00 (2018.01); C07C 317/14 (2013.01); C07D 215/48 (2013.01); C07D 307/16 (2013.01); C07D 307/81 (2013.01); C07D 311/04 (2013.01); C07D 311/76 (2013.01); C07D 317/68 (2013.01); C07D 319/22 (2013.01); C07D 405/12 (2013.01); C07D 407/12 (2013.01); C07C 2601/02 (2017.05); C07C 2601/04 (2017.05); C07C 2601/08 (2017.05); C07C 2601/14 (2017.05); C07C 2602/06 (2017.05); C07C 2602/08 (2017.05); C07C 2602/10 (2017.05);
Abstract

The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.


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