The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2019

Filed:

Jun. 25, 2012
Applicants:

Zhenpeng Yu, Shanghai, CN;

Gouping Wang, Shanghai, CN;

Zhen Zhang, Shanghai, CN;

Minyu Liu, Shanghai, CN;

Xiaoling Huang, Shanghai, CN;

Ying Liu, Shanghai, CN;

Lin Xiao, Shanghai, CN;

LI Cai, Shanghai, CN;

Xuejun Wu, Shanghai, CN;

Yifang Deng, Shanghai, CN;

Mianli Pan, Shanghai, CN;

Renhai Chen, Shanghai, CN;

Shenrong Tang, Shanghai, CN;

Quanhai Liu, Shanghai, CN;

Inventors:

Zhenpeng Yu, Shanghai, CN;

Gouping Wang, Shanghai, CN;

Zhen Zhang, Shanghai, CN;

Minyu Liu, Shanghai, CN;

Xiaoling Huang, Shanghai, CN;

Ying Liu, Shanghai, CN;

Lin Xiao, Shanghai, CN;

Li Cai, Shanghai, CN;

Xuejun Wu, Shanghai, CN;

Yifang Deng, Shanghai, CN;

Mianli Pan, Shanghai, CN;

Renhai Chen, Shanghai, CN;

Shenrong Tang, Shanghai, CN;

Quanhai Liu, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 235/84 (2006.01); A61K 31/165 (2006.01); A61K 31/166 (2006.01); A61K 31/222 (2006.01); C07C 325/02 (2006.01); C07C 235/20 (2006.01); C07C 235/26 (2006.01); C07C 251/24 (2006.01); C07C 231/02 (2006.01);
U.S. Cl.
CPC ...
C07C 235/84 (2013.01); A61K 31/165 (2013.01); A61K 31/166 (2013.01); A61K 31/222 (2013.01); C07C 231/02 (2013.01); C07C 235/20 (2013.01); C07C 235/26 (2013.01); C07C 251/24 (2013.01); C07C 325/02 (2013.01); C07C 2601/02 (2017.05); C07C 2601/14 (2017.05);
Abstract

Disclosed are amide compounds, preparation method and uses thereof, specifically, the compounds represented by formula I or pharmaceutically acceptable salts, wherein R, R, R, R, R, Q, X and n are defined as in the description. Also disclosed are a method for preparing the compounds of formula I, a composition containing the compounds, and the uses of the same in the preparation of medicaments for regulating blood lipid and/or preventing gallstone. The compounds of formula I disclosed in the present invention have stability in vitro, good solubility in the pharmaceutical organic solvents and favorable bioavailability in animals.


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