The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2019

Filed:

May. 27, 2015
Applicant:

Ilumina, Inc., San Diego, CA (US);

Inventors:

Alex Aravanis, San Francisco, CA (US);

Boyan Boyanov, San Diego, CA (US);

M. Shane Bowen, San Diego, CA (US);

Dale Buermann, San Diego, CA (US);

Alexander Hsiao, San Diego, CA (US);

Behnam Javanmardi, San Francisco, CA (US);

Tarun Khurana, San Francisco, CA (US);

Poorya Sabounchi, San Francisco, CA (US);

Hai Quang Tran, San Diego, CA (US);

Assignee:

Illumina, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); F16K 99/00 (2006.01); B01L 7/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502715 (2013.01); B01L 3/502738 (2013.01); B01L 7/525 (2013.01); F16K 99/0013 (2013.01); F16K 99/0015 (2013.01); F16K 99/0028 (2013.01); B01L 2200/025 (2013.01); B01L 2200/027 (2013.01); B01L 2200/04 (2013.01); B01L 2200/0689 (2013.01); B01L 2200/10 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0883 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/1827 (2013.01); B01L 2400/065 (2013.01); B01L 2400/0633 (2013.01); B01L 2400/0638 (2013.01); B01L 2400/0644 (2013.01); B01L 2400/0655 (2013.01); F16K 2099/0074 (2013.01); F16K 2099/0084 (2013.01);
Abstract

Systems and methods for conducting designated reactions utilizing a base instrument and a removable cartridge. The removable cartridge includes a fluidic network that receives and fluidically directs a biological sample to conduct the designated reactions. The removable cartridge also includes a flow-control valve that is operably coupled to the fluidic network and is movable relative to the fluidic network to control flow of the biological sample therethrough. The removable cartridge is configured to separably engage a base instrument. The base instrument includes a valve actuator that engages the flow-control valve of the removable cartridge. A detection assembly held by at least one of the removable cartridge or the base instrument may be used to detect the designated reactions.


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