The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2019

Filed:

Apr. 18, 2014
Applicant:

City of Hope, Duarte, CA (US);

Inventors:

Karen Aboody, Duarte, CA (US);

Alexander Annala, Duarte, CA (US);

Rachael Mooney, Duarte, CA (US);

Jacob Berlin, Duarte, CA (US);

Yiming Weng, Duate, CA (US);

Assignee:

City of Hope, Duarte, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/30 (2015.01); A61K 49/08 (2006.01); A61K 31/4188 (2006.01); A61K 47/51 (2017.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
A61K 35/30 (2013.01); A61K 31/4188 (2013.01); A61K 47/51 (2017.08); A61K 47/6901 (2017.08); A61K 47/6923 (2017.08); A61K 47/6929 (2017.08); A61K 49/085 (2013.01);
Abstract

A therapeutic or diagnostic delivery vehicle is provided. The delivery vehicle may include one or more particles, such as microparticles, nanoparticles and stimuli-responsive particles, conjugated to a tropic cell that targets at least one pathological entity or site. In addition, a pharmaceutical composition is provided. The pharmaceutical composition may include, among other things, a particle conjugated to a tropic cell such as those discussed above and at least one diagnostic or therapeutic agent, such as those described herein. In some aspects, the tropic cell may target at least one pathological entity or site. Further, methods for diagnosing, monitoring or treating a pathological condition in a subject are provided. Such methods may include administering a therapeutically effective amount of the pharmaceutical composition to a subject.


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