The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2019

Filed:

Apr. 11, 2014
Applicant:

The Brigham and Women's Hospital, Inc., Boston, MA (US);

Inventors:

Francisco J. Quintana, Brookline, MA (US);

Ivan D. Mascanfroni, Brighton, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/15 (2015.01); A61K 45/06 (2006.01); A61K 39/00 (2006.01); C07K 14/54 (2006.01); C07K 16/28 (2006.01); C12N 9/14 (2006.01); A61K 47/69 (2017.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
A61K 35/15 (2013.01); A61K 39/00 (2013.01); A61K 39/0008 (2013.01); A61K 45/06 (2013.01); A61K 47/6929 (2017.08); C07K 14/54 (2013.01); C07K 16/2851 (2013.01); C12N 9/14 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/577 (2013.01); C07K 2319/33 (2013.01); C12Y 306/01005 (2013.01);
Abstract

Embodiments of various aspects described herein are directed to methods and compositions for producing a tolerognic or immunosuppressive dendritic cell. In particular, an immunosuppressive dendritic cell can be produced by contacting a dendritic cell with an agent that stimulates the IL 27/ectonucleotidase CD39 axis signaling. In some embodiments, the methods and/or compositions described herein can be used for treating an autoimmune disease or disorder, e.g., but not limited to multiple sclerosis (MS) and type 1 diabetes.


Find Patent Forward Citations

Quintana, Francisco. (2019). Methods and compositions of treating autoimmune diseases (U.S. Patent No. 10426794). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10426794

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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